Molecular BiologyThe EMBO JournalPeer-reviewed
Replication-induced DNA secondary structures drive fork uncoupling and breakage
Sophie L. Williams, Corella S. Casas-Delucchi, Federica Raguseo…·Gideon Coster
This study shows that DNA secondary structures like G4s and iMs cause replication fork arrest and breakage, and that Pif1 helicase is required to resolve stalled forks.
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