Cancer BiologybioRxivPreprint
A potent and selective TNKS2 inhibitor for tumor-selective WNT suppression
Jill Zimmerman, Brandon F Malone, Efrat Finkin-Groner…·Lukas E. Dow
The paper identifies a TNKS2-selective inhibitor that enables tumor-selective WNT suppression by exploiting 8p loss in cancer cells.
DOI 10.1101/2025.03.04.641305