Author

Zhen W. Zhuang

Yale UniversityORCID 0000-0002-1515-8543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1

Frequent Co-Authors

A. JustetiD· 1 shared Abhay B. RamachandraiD· 1 shared Chao Dong· 1 shared Cristina CavinatoiD· 1 shared Edward P. ManningiD· 1 shared Fadi Nikola· 1 shared George TellidesiD· 1 shared Hui‐Chun HuangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

A. JustetORCID

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2 papers

Recent·Most cited

PathologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2026

Hepatic Arterial Flow-Induced Portal Tract Fibrosis in Portal Hypertension: The Role of VCAM-1 and Osteopontin-Expressing Macrophages

Ruixue Ma, Li Gong, Chao Dong…·Yasuko Iwakiri

This study shows that increased VCAM-1 in hepatic artery endothelial cells and portal fibroblasts recruits Spp1+ macrophages, driving fibrosis in portal hypertension.

4 citationstop 2%

ratbulk RNA-seq

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PhysiologybioRxivPreprintFeb 15, 2025

Hypoxia-Induced Cardiopulmonary Remodeling and Recovery: Critical Roles of the Proximal Pulmonary Artery, Macrophages, and Exercise

Abhay B. Ramachandra, Prapti Sharma, Ruben De Man…·Edward P. Manning

This study examines hypoxia-induced cardiopulmonary remodeling in mice, finding that pulmonary artery stiffening due to collagen remodeling precedes and correlates with cardiac and lung dysfunction, with partial recovery observed after normoxia.

5 citations

mouseimaging

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