NeurosciencebioRxivPreprint
Isogenic forebrain organoids uncover early neurodevelopmental alterations and imbalances in neuronal function leading to hyperexcitation in Gaucher disease
James A Crowe, Zuzana Matusova, Aline S Girard…·Isaac Canals
This study uses isogenic brain organoids to identify early neurodevelopmental changes and hyperexcitability in Gaucher disease, linking lipid dysregulation and neuronal function imbalances to clinical symptoms.