Author

James A Crowe

King's College LondonORCID 0000-0003-4487-9048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessio CremonesiiD· 1 shared Aline S Girard· 1 shared Amélie RajoniD· 1 shared Amjad Hasan BazzariiD· 1 shared Anthony Christopher VernoniD· 1 shared Clàudia Puigsasllosas PastoriD· 1 shared Daniel TorneroiD· 1 shared David A. NageliD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Alessio CremonesiORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 29, 2026

Isogenic forebrain organoids uncover early neurodevelopmental alterations and imbalances in neuronal function leading to hyperexcitation in Gaucher disease

James A Crowe, Zuzana Matusova, Aline S Girard…·Isaac Canals

This study uses isogenic brain organoids to identify early neurodevelopmental changes and hyperexcitability in Gaucher disease, linking lipid dysregulation and neuronal function imbalances to clinical symptoms.

DOI 10.64898/2026.09.27.754744

humanscRNA-seq

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NeurosciencebioRxivPreprintNov 1, 2024

Astrocytes control UP state and slow oscillation periodicity in human cortical networks

James A Crowe, Amjad Hasan Bazzari, David A. Nagel…·H. Rheinallt Parri

This study shows astrocytes regulate slow oscillation periodicity and UP state in human cortical networks through calcium signaling and neurotransmitter pathways.

1 citation

humanexperimental assay

𝕏 PostBluesky

NeuroscienceMolecular AutismPeer-reviewedJan 22, 2021

Application of Airy beam Light sheet microscopy to examine early neurodevelopmental structures in 3D hiPSC-derived human cortical spheroids

Dwaipayan Adhya, George Chennell, James A Crowe…·Deepak P. Srivastava

This paper optimizes Airy-beam light sheet microscopy to image 3D structures in hiPSC-derived human cortical spheroids, enabling high-resolution analysis of neurodevelopmental processes.

24 citations

humanimaging

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