Author

Daniel Tornero

Biomedical Research Networking Center on Neurodegenerative DiseasesORCID 0000-0002-4812-4091Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adriana Modrego· 1 shared Alba Ortega-GascóiD· 1 shared Alessio CremonesiiD· 1 shared Aline S Girard· 1 shared Amélie RajoniD· 1 shared Andrea Martí-SarriasiD· 1 shared Anna-Christina HaebiD· 1 shared Arcadi NavarroiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Adriana Modrego

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2 papers

Recent·Most cited

Isogenic forebrain organoids uncover early neurodevelopmental alterations and imbalances in neuronal function leading to hyperexcitation in Gaucher disease

James A Crowe, Zuzana Matusova, Aline S Girard, Amélie Rajon, David Colameo, Leal Oburoglu, Oskar G. Zetterdahl, Joachim Björklund, Clàudia Puigsasllosas Pastor, Svenja Krupp, Ulf Ellervik, Alessio Cremonesi, Daniel Tornero, David Pentón, Henrik Ahlenius, , Isaac Canals

This study uses isogenic brain organoids to identify early neurodevelopmental changes and hyperexcitability in Gaucher disease, linking lipid dysregulation and neuronal function imbalances to clinical symptoms.

bioRxiv · Sep 29, 2026 · PreprintNeuroscience

Variability vs Phenotype: multimodal analysis of Dravet Syndrome Brain Organoids powered by Deep Learning

Isabel Turpín, Adriana Modrego, Andrea Martí-Sarrias, Laura García‐González, Alba Ortega-Gascó, Anna-Christina Haeb, Ruth I. Pareja, Jordi Soriano, Nuria Ruíz, Irene Peñuelas‐Haro, Elisa Espinet, Arcadi Navarro, Daniel Tornero, Óscar Lao, Sandra Acosta

The paper develops ImPheNet, a deep learning tool to classify phenotypes and assess drug toxicity in Dravet Syndrome brain organoids using live imaging data.

iScience · Oct 23, 2025Peer-reviewedDevelopmental Biology