Pyroptotic cell-derived factors promote osteoclast differentiation
Yongjia Li, Chun Wang, 许灿新…·许灿新
This study shows that NLRP3CA-induced pyroptosis releases soluble proteins that promote osteoclast differentiation independently of IL-1β.
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Washington University in St. LouisORCID 0000-0002-1538-2019Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Yongjia Li, Chun Wang, 许灿新…·许灿新
This study shows that NLRP3CA-induced pyroptosis releases soluble proteins that promote osteoclast differentiation independently of IL-1β.
Khushpreet Kaur, Yael Alippe, Chun Wang…·Gabriel Mbalaviele
The paper shows Tmem178 suppresses NLRP3 inflammasome activation in osteoclasts by limiting calcium release, preventing excessive bone resorption.
Nitin Kumar Pokhrel, Amanda R. Panfil, Haniya Habib…·Deborah V. Novack
This study shows HTLV-1 infected T cells release small extracellular vesicles that promote bone loss by stimulating osteoclasts, independent of RANKL expression.