Cell BiologyPharmacology Research & PerspectivesPeer-reviewed
β-adrenergic blockers increase cAMP and stimulate insulin secretion through a PKA/RYR2/TRPM5 pathway in pancreatic β-cells in vitro
5 citations
Author
Kenju Shimomura
Fukushima Medical UniversityORCID 0000-0002-1539-2532Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2023-2025 · peak 2/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship4 papers
Recent·Most cited
- Cell BiologyThe FASEB JournalPeer-reviewed
Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion
Naoya Murao, Risa Morikawa, Yusuke Seino…·Atsushi Suzuki
This study identifies pyruvate kinase as a key regulator linking β-cell fructose metabolism and insulin secretion, showing that a PK activator can restore fructose-stimulated insulin secretion in diabetic models.
5 citations - Cell BiologyPhysiological ReportsPeer-reviewed
Sildenafil amplifies calcium influx and insulin secretion in pancreatic β cells
Naoya Murao, Risa Morikawa, Yusuke Seino…·Atsushi Suzuki
This study shows sildenafil enhances insulin secretion in pancreatic β cells by increasing calcium influx, independent of L-type Ca2+ channels and PDE5.
3 citations - NeurosciencebioRxivPreprint
Chemogenetic activation of target neurons expressing insect Ionotropic Receptors in the mammalian central nervous system by systemic administration of ligand precursors
Yoshio Iguchi, Ryoji Fukabori, Shigeki Kato…·Kazuto Kobayashi
This paper develops a method to activate specific neurons in the mammalian brain using peripheral administration of ligand precursors, demonstrating its effectiveness in inducing neurotransmitter release and behavioral responses.