Author

Natalia López‐González del Rey

HM HospitalesORCID 0000-0002-1546-1825Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alejandro Rojas‐FernándeziD· 2 shared Constanza Salinas-RebolledoiD· 2 shared David SchwefeliD· 2 shared Guillermo ValenzuelaiD· 2 shared Javier BlesaiD· 2 shared Pedro Chaná‐CuevasiD· 2 shared Ronald JaraiD· 2 shared Alberto Anastacio AmarillaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Alejandro Rojas‐FernándezORCID

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2 papers

Recent·Most cited

BiochemistryeLifePeer-reviewedNov 25, 2025

Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

Constanza Salinas-Rebolledo, Javier Blesa, Guillermo Valenzuela…·Alejandro Rojas‐Fernández

This paper describes the engineering of a PROTAC that uses p97-directed proteolysis to achieve specific substrate degradation without relying on E3 ubiquitin ligases.

3 citations

proteomicsexperimental assay

𝕏 PostBluesky

Molecular BiologyScientific ReportsPeer-reviewedFeb 8, 2021

Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity Nanobody.

Guillermo Valenzuela, Ronald Jara, Daniel Watterson…·Alejandro Rojas‐Fernández

The paper describes the development of a high-affinity Nanobody against SARS-CoV-2 RBD that neutralizes wild-type and D614G variants with nanomolar potency.

57 citations

proteomicsexperimental assay

𝕏 PostBluesky