Author
Technische Universität BerlinORCID 0000-0002-2945-0908Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Constanza Salinas-Rebolledo, Javier Blesa, Guillermo Valenzuela…·Alejandro Rojas‐Fernández
This paper describes the engineering of a PROTAC that uses p97-directed proteolysis to achieve specific substrate degradation without relying on E3 ubiquitin ligases.
Fabian Schildhauer, Petra S. J. Ryl, Simon Malte Lauer…·Juri Rappsilber
The paper identifies AIFM1/AK2 interaction as a gatekeeper of mitochondrial ATP synthase, showing it is NADH-dependent and linked to metabolic state, with implications for mitochondrial diseases.
Ekaterina V. Borisova, Katherine J. Cuthill, Rike Dannenberg…·Mateusz C. Ambrozkiewicz
The paper shows UBE3C regulates cortical neurogenesis and glial fate through m6A methylation, with mutations disrupting this process and offering therapeutic targets.
Guillermo Valenzuela, Ronald Jara, Daniel Watterson…·Alejandro Rojas‐Fernández
The paper describes the development of a high-affinity Nanobody against SARS-CoV-2 RBD that neutralizes wild-type and D614G variants with nanomolar potency.