Author
Austral University of ChileORCID 0000-0002-6220-504XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Constanza Salinas-Rebolledo, Javier Blesa, Guillermo Valenzuela…·Alejandro Rojas‐Fernández
This paper describes the engineering of a PROTAC that uses p97-directed proteolysis to achieve specific substrate degradation without relying on E3 ubiquitin ligases.
Ariel Isaacs, Guillermo Valenzuela, Xinghai Zhang…·Daniel Watterson
This paper develops a bispecific antibody that targets both Nipah virus surface glycoproteins, reducing viral escape and enhancing protection against NiV disease.
Eduardo A. Albornoz, Alberto Anastacio Amarilla, Naphak Modhiran…·Trent M. Woodruff
This study shows SARS-CoV-2 activates microglial NLRP3 inflammasome via spike-ACE2 interaction, potentially linking viral infection to neurological symptoms like Parkinson's.
Guillermo Valenzuela, Ronald Jara, Daniel Watterson…·Alejandro Rojas‐Fernández
The paper describes the development of a high-affinity Nanobody against SARS-CoV-2 RBD that neutralizes wild-type and D614G variants with nanomolar potency.