Daniel Watterson

This study examines immune dynamics in lymph nodes after YFV-17D vaccination, identifying robust B and T cell responses and a conserved germinal center program across different vaccines.

This study shows that DENV infection in mice causes gut barrier damage, bacterial translocation, and dysbiosis, which contribute to liver inflammation and disease severity.

This study identifies an IgG3 subclass antibody that expands neutralization breadth against dengue and zika viruses by engaging a quaternary epitope through structural and functional analyses.

The paper generates antigen-specific recombinant bat antibodies from Pteropus alecto to study bat antibody immunity and provides new diagnostic tools.

The paper evaluates vaccine-induced and hybrid immunity against SARS-CoV-2 variants in two cohorts, finding reduced antibody titres and neutralization activity against Omicron variants, with some recovery after multiple vaccinations.

This paper develops a bispecific antibody that targets both Nipah virus surface glycoproteins, reducing viral escape and enhancing protection against NiV disease.

This study shows senolytic drugs reduce brain aging and COVID-19-related neuropathology by targeting senescent cells in human brain organoids and mice.

This study shows SARS-CoV-2 activates microglial NLRP3 inflammasome via spike-ACE2 interaction, potentially linking viral infection to neurological symptoms like Parkinson's.

The paper uses long-read sequencing to investigate SARS-CoV-2 integration into the human genome and finds no evidence of such integration in infected cells.

The paper describes the development of a high-affinity Nanobody against SARS-CoV-2 RBD that neutralizes wild-type and D614G variants with nanomolar potency.