Author

Stephan George

Boston Children's HospitalORCID 0000-0002-1601-0567Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Julia Goldstein· 2 shared Trista E. NorthiD· 2 shared Wade W. SugdeniD· 2 shared Allison Tompkins· 1 shared Berkley E. GryderiD· 1 shared Brianna Badalamenti· 1 shared Brittney D. LoveiD· 1 shared Calum A. MacRaeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Julia Goldstein

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Flow-Induced Yap/Taz Signaling Balances Endothelial and Hematopoietic Stem Cell Fates

Wade W. Sugden, Stephan George, Zachary C. LeBlanc, Morgan T. Walcheck, Eleanor Meader, Julia Goldstein, Elizabeth Molnar, Wandi Zhu, Rubul Mout, Christopher Li, Leah Radeke, Zoey Young, Maria Gonzalez di Tillio, Marcelo Falchetti, Mohamad Ali Toufic Najia, , Trista E. North

This study shows that hemodynamic forces activate YAP signaling via Piezo1 in hemogenic endothelium, promoting HSC production by regulating metabolic and gene regulatory programs, while TAZ overactivation disrupts this balance.

bioRxiv · Jun 23, 2026 · PreprintCell Biology

Dynamic activity of Erg promotes aging of the hematopoietic system

Mayuri Tanaka-Yano, Wade W. Sugden, Dahai Wang, Brianna Badalamenti, Parker Côté, Diana H. Chin, Julia Goldstein, Stephan George, Gabriela Flavia Rodrigues-Luiz, Edroaldo Lummertz da Rocha, Hojun Li, Trista E. North, Berkley E. Gryder, R. Grant Rowe

This study identifies Erg as a master transcription factor whose upregulation during aging is critical for adult hematopoietic stem cell function and resistance to leukemogenesis.

bioRxiv · Jan 23, 2025 · PreprintDevelopmental Biology