Author
Boston Children's HospitalORCID 0000-0002-7000-4184Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Wade W. Sugden, Stephan George, Zachary C. LeBlanc…·Trista E. North
This study shows that hemodynamic forces activate YAP signaling via Piezo1 in hemogenic endothelium, promoting HSC production by regulating metabolic and gene regulatory programs, while TAZ overactivation disrupts this balance.
Eleanor Meader, Morgan T. Walcheck, Mindy Leder…·Trista E. North
This study shows that Bnip3lb-driven mitophagy maintains embryonic HSPC multipotency and expansion by regulating ROS levels, and enhances ex vivo hematopoietic potential of iPSC-derived HSPCs.
Mohamad Ali Toufic Najia, Deepak Kumar Jha, Cheng Zhang…·George Q. Daley
The paper identifies KDM4 demethylase inhibition as a therapeutic strategy for lymphoma and other cancers by rewiring heterochromatin and inducing DNA damage.