MicrobiologybioRxivPreprint
N6-methyladenosine (m6A) RNA modification restrains antifungal immunity and is a therapeutic target in oral candidiasis
Nicole O. Ponde, Melissa Erin Cook, Isha Mehta…·Sarah L. Gaffen
This study shows that m6A RNA modification suppresses antifungal immunity in oral epithelial cells and that inhibiting the m6A pathway enhances antimicrobial peptide expression, reducing fungal burden in candidiasis.