ImmunologyPLoS PathogensPeer-reviewed
An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen
Bianca M. Coleman, Melissa Erin Cook, Md. Robin Khan…·Sarah L. Gaffen
1 citation
Author
Melissa Erin Cook
University of PittsburghORCID 0000-0002-2336-956XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2025-2026 · peak 2/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship3 papers
Recent·Most cited
- ImmunologyNature CommunicationsPeer-reviewed
Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance
Nicolas Millet, Jinendiran Sekar, Norma V. Solis…·Marc Swidergall
This study shows that fungal-induced immunosurveillance remodels the oral mucosal barrier via a non-canonical IL-22 receptor complex, enhancing resistance to Candida albicans colonization.
6 citationstop 1% - MicrobiologybioRxivPreprint
N6-methyladenosine (m6A) RNA modification restrains antifungal immunity and is a therapeutic target in oral candidiasis
Nicole O. Ponde, Melissa Erin Cook, Isha Mehta…·Sarah L. Gaffen
This study shows that m6A RNA modification suppresses antifungal immunity in oral epithelial cells and that inhibiting the m6A pathway enhances antimicrobial peptide expression, reducing fungal burden in candidiasis.