Wei Ting Wang

This study identifies FRMD8 as a regulator of tmTNF-α processing in breast cancer metastasis, showing its role in modulating ADAM17 activity and TNF-α dynamics.

This paper introduces OPERA, a method for detecting low-frequency mutations in short and rare cell-free DNA, achieving higher sensitivity than existing methods.

This paper uses self-reported medical data to perform GWAS on 33 rare diseases, rediscovering known associations and finding novel ones, validated across multiple populations.

The paper develops an extended motif finding pipeline to identify de novo methylated DNA motifs in Arabidopsis and human cell lines, revealing novel motifs recognized by transcription factors or their co-factors.

The paper expands DNA methylation data from TCGA using EAGLING, identifies triple-evidenced genes across 13 cancers, and reveals enriched pathways with potential therapeutic value.