Author

Dounia Le Guillou

University of California, San FranciscoORCID 0000-0002-1614-5381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jacquelyn J. MaheriD· 2 shared Antonio Munoz-Howell· 1 shared Aras N. MattisiD· 1 shared Caroline C. DuwaertsiD· 1 shared Chris L Her· 1 shared Elizabeth TheuschiD· 1 shared Grace Lim· 1 shared Kevin SiaoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Jacquelyn J. MaherORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyStem Cells Translational MedicinePeer-reviewedNov 9, 2025

Predicting Metabolic Dysfunction Associated Steatotic Liver Disease Risk Using Patient-Derived Induced Pluripotent Stem Cells

Yuanyuan Qin, Parth D. Chhetri, Elizabeth Theusch…·Marisa Wong Medina

This paper develops an iPSC-based risk predictor for MASLD using lipid accumulation measurements and validates it across three cohorts with varying performance.

2 citations

humanexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintAug 27, 2025

iPSC-Derived Hepatocytes from Patients with MASLD Exhibit Early Mitochondrial Dysfunction

Dounia Le Guillou, Kevin Siao, Chris L Her…·Jacquelyn J. Maher

This study shows that iPSC-derived hepatocytes from MASLD patients show early mitochondrial dysfunction, including reduced oxygen consumption and increased ROS production, independent of PNPLA3 genotype.

1 citation

humanscRNA-seq

𝕏 PostBluesky