Author

Wook‐Jin Chae

Virginia Commonwealth UniversityORCID 0000-0002-1618-0654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Theingi Aung· 2 shared Eun‐Ah SungiD· 1 shared Hisashi HaradaiD· 1 shared Joyce Kasongo· 1 shared Mikhail G. DozmoroviD· 1 shared Min Hee ParkiD· 1 shared Octavian HenegariuiD· 1 shared Patricia J. SimeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Theingi Aung

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2 papers

Recent·Most cited

ImmunologyThe Journal of ImmunologyPeer-reviewedFeb 1, 2026

Dickkopf1 is a Novel Endogenous Ligand for priming NLRP3 Inflammasome in Macrophages via TLR4

Theingi Aung, SuJeong Song, Joyce Kasongo…·Wook‐Jin Chae

This study identifies DKK1 as a novel endogenous ligand that primes macrophages via TLR4 to activate NLRP3 inflammasome and induce pyroptosis, distinct from LPS signaling.

1 citation

humanmouse

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PathologyFEBS LettersPeer-reviewedJan 28, 2025

Ablation of LRP6 in alpha-smooth muscle actin-expressing cells abrogates lung inflammation and fibrosis upon bleomycin-induced lung injury

Eun‐Ah Sung, Mikhail G. Dozmorov, Su-Jeong Song…·Wook‐Jin Chae

This study shows that deleting LRP6 in SMA-expressing cells prevents lung inflammation and fibrosis caused by bleomycin.

1 citation

mouseexperimental assay

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