Patrick D’Silva

The paper identifies a novel apoptotic pathway regulated by the TIM22 complex and Nde1, showing that disrupting this pathway suppresses apoptosis and improves mitochondrial health.

This study identifies a novel interaction between mutant SOD1 and the TIM23 complex in yeast, revealing its role in mitochondrial dysfunction and ALS pathogenesis.

This study identifies AtDJ-1C and AtDJ-1E as critical antioxidants in Arabidopsis thaliana that enhance survival under heat and oxidative stress by regulating redox homeostasis and improving plant growth.

This study identifies a functional interaction between Ubp2 and DJ-1 paralogs in Saccharomyces cerevisiae that regulates mitochondrial homeostasis and oxidative stress resistance.