Author
University of Colorado BoulderORCID 0000-0002-1642-9632Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Alison C. Leonard, Chase Lenert-Mondou, Rachel Chayer…·Timothy A. Whitehead
The paper designs dynamic biosensors for detecting nitazenes and their metabolites using computational methods, achieving low nanomolar detection limits and limited cross-reactivity.
Nicholas R. Robertson, Chase Lenert-Mondou, Alison C. Leonard…·Ian R. Wheeldon
The paper uses a PYR1 biosensor-driven CRISPR screen in Kluyveromyces marxianus to identify gene knockouts that enhance geraniol production by up to 2-fold.
Alison C. Leonard, Anika J. Friedman, Rachel Chayer…·Timothy A. Whitehead
This study analyzes two engineered biosensors based on PYR1 to recognize different ligands, revealing binding mechanisms and computational methods for biosensor design.