Ke Li

The paper develops DeepDelivery, an AI platform that identifies human proteins for mRNA delivery, validating 80% of top candidates for efficient, non-inflammatory delivery.

This study identifies a PP4-dependent mechanism for Hop1 and Red1 assembly onto meiotic chromatin in budding yeast, independent of DSB formation.

The paper shows that downstream out-of-frame AUGs inhibit translation initiation at the annotated AUG, with diminishing effect over distance, supporting a Brownian ratchet model of ribosome scanning.

This study uses single-cell RNA sequencing to analyze rice cell responses to abiotic stresses, identifying cell-type-specific gene expression changes and population dynamics.

This study shows that the Ecm11-Gmc2 complex modulates crossover pathways and suppresses non-crossover recombination during meiosis in budding yeast.

The paper shows that overdosage of balanced protein complexes reduces proliferation in aneuploid yeast and human cancer cells.