Miki Shinohara

Meiotic DSB-independent role of protein phosphatase 4 in Hop1 assembly to promote meiotic chromosome axis formation in budding yeast

This study identifies a PP4-dependent mechanism for Hop1 and Red1 assembly onto meiotic chromatin in budding yeast, independent of DSB formation.

Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis

This study identifies phosphorylation of Mps3's luminal region as critical for its nuclear envelope localization during meiosis, mediated by CDK and DDK.

The Synaptonemal Complex Central Region Modulates Crossover Pathways and Feedback Control of Meiotic Double-strand Break Formation

This study shows that the Ecm11-Gmc2 complex modulates crossover pathways and suppresses non-crossover recombination during meiosis in budding yeast.

SCFCdc4 ubiquitin ligase regulates synaptonemal complex formation during meiosis

This study shows that SCFCdc4 ubiquitin ligase regulates synaptonemal complex formation during meiosis, collaborating with Pch2 and affecting meiotic recombination.

The bakerss yeast Msh4-Msh5 associates with double-strand break hotspots and chromosome axis during meiosis to promote crossovers

The paper investigates the in vivo localization of Msh5 during meiosis in yeast, showing its association with DSB hotspots, chromosome axis, and centromeres, and its role in promoting crossover formation.

DNA damage response clamp loader Rad24(Rad17) and Mec1(ATR) kinase have distinct functions in regulating meiotic crossovers

This study shows that Rad24/Rad17 and Mec1/ATR have distinct roles in regulating meiotic crossovers, with Rad24 affecting CO frequency on shorter chromosomes and Mec1 impacting CO interference.

Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis