Feng Qiao

The paper identifies a conserved sequence motif that enables natural enzymes to use non-canonical redox cofactors, demonstrating high activity with NMN+ and other synthetic cofactors.

The paper identifies sequence-specific sensitivity to JTE-607 in mRNA 3' processing by analyzing over 260,000 sequence variants and developing a predictive model.

The paper uses proteomics to show that β-hydroxybutyrylation of proteins in mouse liver under ketogenic conditions affects metabolic pathways and enzyme function.

The paper investigates how cooperative assembly of the shelterin bridge regulates telomere length homeostasis by acting as a molecular timer.