Author

Shengyi Sun

University of VirginiaORCID 0000-0002-1734-3902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Ling QiiD· 2 shared Hui WangiD· 1 shared Huilun Helen WangiD· 1 shared Liangguang Leo LiniD· 1 shared Lulu JiangiD· 1 shared Mauricio TorresiD· 1 shared Muge N. Kuyumcu‐MartineziD· 1 shared Sijie HaoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Ling QiORCID

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2 papers

Recent·Most cited

Synergistic Control of Mitochondrial Dynamics and Function by ERAD and Autophagy in Brown Adipocytes

Xinxin Chen, Siwen Wang, Mauricio Torres, Sijie Hao, Shengyi Sun, Ling Qi

This study reveals a synergy between SEL1L-HRD1 ERAD and autophagy in maintaining mitochondrial structure and thermogenic capacity in brown adipocytes.

bioRxiv · Jun 14, 2025 · PreprintCell Biology

Functional rescue of a fatal ERAD mutation via alternative splicing

Huilun Helen Wang, Zhihong Wang, Liangguang Leo Lin, Sunil Kumar Verma, Weronika Gniadzik, Hui Wang, Zexin Jason Li, Lulu Jiang, Muge N. Kuyumcu‐Martinez, Shengyi Sun, Ling Qi

This study reports the discovery of using antisense oligonucleotides (ASOs) to rescue the biallelic SEL1L C141Y variant, offering a potential therapeutic strategy.

bioRxiv · Jun 13, 2025 · PreprintCell Biology