Author

Yifei Guo

Oregon Health & Science UniversityORCID 0000-0002-1744-0227Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexandra Q. BartlettiD· 2 shared Canping CheniD· 2 shared Hen HalamishiD· 2 shared Jennifer M. FinaniD· 2 shared Jonathan Robert BrodyiD· 2 shared Kevin HawthorneiD· 2 shared Rosalie C. SearsiD· 2 shared Zheng XiaiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Alexandra Q. BartlettORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Post-transcriptional regulator HuR promotes immune evasion in pancreatic ductal adenocarcinoma

Yifei Guo, Jennifer M. Finan, Alexandra Q. Bartlett, Katherine R. Pelz, Shamilene Sivagnanam, Katie E. Blise, Nell C. Kirchberger, Konjit Betre, Yuhui Wei, Jennifer R. Eng, Vidhi M. Shah, Canping Chen, Grace A. McCarthy, Hen Halamish, Kevin Hawthorne, , Robert L Eil

This study shows that HuR promotes immune evasion in PDAC by inhibiting T cell infiltration and function, suggesting HuR as a therapeutic target with immunotherapy.

Journal for ImmunoTherapy of Cancer · Nov 1, 2025Peer-reviewedCancer Biology

Pancreatic cancer-intrinsic HuR regulates the pro-tumorigenic properties of extracellular vesicles

Jennifer M. Finan, Yifei Guo, Alexandra Q. Bartlett, Matthew Reyer, Kevin Hawthorne, Margaret E. Haerr, Hen Halamish, Olayinka Lamikanra, Valerie S. Calvert, Canping Chen, Zheng Xia, Emanuel F. Petricoin, Rosalie C. Sears, Katelyn T. Byrne, Jonathan Robert Brody

This study shows that HuR in pancreatic cancer cells enhances angiogenesis by modulating extracellular vesicle signaling to endothelial cells, increasing their migratory and tube-forming abilities while reducing ICAM-1 expression.

bioRxiv · Feb 8, 2025 · PreprintCancer Biology