David Artis

Diverse infections transcriptionally reprogram the intestinal epithelium and epithelial-immune cell interactions

The paper creates a single-cell and spatial transcriptomics atlas of the ileum during diverse infections, revealing novel cell states and immune responses.

Omics-scale capture of electrophilic metabolites

This paper introduces TAMOHA, a biochemical probe that enables comprehensive profiling of electrophilic metabolites, revealing thousands of previously uncharacterized species in E. coli, C. elegans, and mouse.

Charting the small-molecule universe from mass spectra with neuro-symbolic AI

AIMe uses neuro-symbolic AI to predict and annotate small-molecule spectra, expanding the searchable chemical space by three orders of magnitude.

Chlamydia muridarum Infection Impacts Murine Models of Intestinal Inflammation and Cancer

This study shows that Chlamydia muridarum infection affects different models of intestinal inflammation and cancer in mice, with varying outcomes depending on the model.

Simultaneous single cell measurements of intranuclear proteins and gene expression

The paper introduces inCITE-seq, a method for simultaneous measurement of intranuclear proteins and gene expression in single cells, and demonstrates its application in analyzing neuronal activity in mouse brain tissue.