A biological light sheet links cellular voltage to mesoscopic brain dynamics
This paper introduces SPress, a method that enables high-speed, high-contrast voltage imaging of large neuronal populations in vivo with mesoscopic resolution.
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National Yang Ming Chiao Tung UniversityORCID 0000-0002-1755-1664Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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This paper introduces SPress, a method that enables high-speed, high-contrast voltage imaging of large neuronal populations in vivo with mesoscopic resolution.
En-Li Chen, Tsai‐Wen Chen, Eric R. Schreiter, Bei‐Jung Lin
The paper investigates synchronous neuronal ensembles in hippocampal CA1 pyramidal neurons during novel exploration and finds they are phase-locked to theta waves and correlate with place cell activity.
Tsai‐Wen Chen, Xianbin Huang, Sarah E. Plutkis…·Bei‐Jung Lin
This paper introduces a method to image neuronal voltage with super-resolution beyond tissue scattering limits, achieving high precision in dense neuronal populations.
Ahmed S. Abdelfattah, Jihong Zheng, Amrita Singh…·Ilya Kolb
The paper identifies a mutation that enhances the sensitivity of a fluorescent voltage indicator, improving its ability to detect both spiking and subthreshold voltage signals in multiple organisms.
Ziqiang Wei, Bei‐Jung Lin, Tsai‐Wen Chen…·Shaul Druckmann
The paper compares neuronal population dynamics measured via calcium imaging and electrophysiology, finding discrepancies that are partially resolved by spike inference algorithms and highlighting the value of forward modeling.
Ahmed S. Abdelfattah, Takashi Kawashima, Amrita Singh…·Eric R. Schreiter
The paper introduces a new genetically encoded voltage indicator, Voltron, which improves brightness and photostability for extended in vivo voltage imaging in mice, zebrafish, and fruit flies.