Ziqiang Wei

The paper identifies a neuron-glia circuit in zebrafish that anticipates hypoxia by integrating behavioral intent and physiological state to prevent internal oxygen depletion.

The paper shows that astrocyte activity drives brainwide changes in sensory, integrative, and motor computations during a passive state in zebrafish.

The paper uses voltage imaging to show how serotonergic neurons in the raphe encode action outcomes and modulate motor vigor during learning in larval zebrafish.

The paper develops an all-optical system to study whole-brain neuronal dynamics during gut interoception in zebrafish, revealing how nutrient delivery and sensory stimuli are encoded across brain regions.

The paper develops fast and sensitive GCaMP indicators for neural activity imaging, achieving ultra-fast kinetics and high sensitivity.

This study evaluates dimensionality reduction methods for calcium imaging data and introduces CILDS, which outperforms existing methods in recovering low-dimensional neural activity.

The paper identifies a brainstem circuit in larval zebrafish that integrates optic flow to maintain positional homeostasis by modulating cerebellar activity.

The paper compares neuronal population dynamics measured via calcium imaging and electrophysiology, finding discrepancies that are partially resolved by spike inference algorithms and highlighting the value of forward modeling.

The paper analyzes neural population dynamics in mouse frontal cortex during decision-making to reveal structure predicting behavioral variability.

The paper develops a biophysically detailed in silico model of layer 4 of the mouse primary visual cortex, showing how functional synaptic connectivity reproduces experimental observations of neuronal responses to visual stimuli.