Author

Megan L. Noonan

Indiana University IndianapolisORCID 0000-0002-1763-1867Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Kenneth E. WhiteiD· 2 shared Adrianna N. Masterson· 1 shared Alexander G. RoblingiD· 1 shared Andrei Bonteanu· 1 shared Christian S. WrightiD· 1 shared Danielle JanoseviciD· 1 shared Danielle WuiD· 1 shared Emmanuel Solis· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

Kenneth E. WhiteORCID

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2 papers

Recent·Most cited

Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets

Rafiou Agoro, Jered Myslinski, Yamil G. Marambio, Danielle Janosevic, Kayleigh Nicole Jennings, Sheng Liu, Lainey M. Hibbard, Fang Fang, Pu Ni, Megan L. Noonan, Emmanuel Solis, Xiaona Chu, Yue Wang, Pierre C. Dagher, Yunlong Liu, , Kenneth E. White

This study uses single-cell transcriptomics to analyze FGF23 bioactivity and identify novel inflammatory targets in the kidney, revealing interactions between FGF23 and TNF/NF-κB pathways.

Kidney International · May 28, 2024Peer-reviewedPhysiology

Gabapentin Disrupts Binding of Perlecan to the α2δ1 Voltage Sensitive Calcium Channel Subunit and Impairs Skeletal Mechanosensation

Perla Citlali Reyes Fernandez, Christian S. Wright, Adrianna N. Masterson, Xin Yi, Tristen V. Tellman, Andrei Bonteanu, Katie Rust, Megan L. Noonan, Kenneth E. White, Karl J. Lewis, Uma Sankar, Julia M. Hum, Gregory Jaye Bix, Danielle Wu, Alexander G. Robling, , William R. Thompson

This study identifies a novel mechanosensory complex in osteocytes involving perlecan and α2δ1 subunit, showing that gabapentin disrupts their interaction and impairs bone mechanosensation.

Biomolecules · Dec 12, 2022Peer-reviewedMolecular Biology