Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
Collette A. LaVigne, Jaeil Han, He Zhang…·Joshua T. Mendell
The paper identifies Plagl1 and Lrrc58 as trigger RNAs that induce degradation of miR-322-5p and miR-503-5p, leading to growth restriction in mice.