Author
University of Michigan
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
Chen Sun, Kunal Kathuria, Sarah B. Emery, Byung-Jun Kim, Ian E. Burbulis, Joo Heon Shin, Brain Somatic Mosaicism Network, Daniel R. Weinberger, John V. Moran, Jeffrey M. Kidd, Ryan E. Mills, Michael J. McConnell
The paper identifies and validates copy number variants in single human neurons using a new method, revealing nonrandom CNV locations and complex karyotypes in a subset of neurons.
bioRxiv · Mar 7, 2023 · PreprintNeuroscience
Xiaoxu Yang, Xin Xu, Martin W. Breuss, Danny Antaki, Laurel Ball, Changuk Chung, Jiawei Shen, Chen Li, Renee D. George, Yifan Wang, Taejeong Bae, Yuhe Cheng, Alexej S. Abyzov, Liping Wei, Ludmil B. Alexandrov, , Sarah B. Emery
DeepMosaic detects mosaic single nucleotide variants without control samples using deep convolutional neural networks, achieving high accuracy and uncovering many variants missed by existing methods.
Nature Biotechnology · Jan 2, 2023Peer-reviewedGenomics
Vidhya Jagannathan, Christophe Hitte, Jeffrey M. Kidd, Patrick Masterson, Terence D. Murphy, Sarah B. Emery, Brian W. Davis, Reuben M. Buckley, Yanhu Liu, Xiangquan Zhang, Tosso Leeb, Ya‐Ping Zhang, Elaine A. Ostrander, Guodong Wang
The paper presents an improved long-read assembly of the dog reference genome, significantly enhancing contiguity and gene annotation.
bioRxiv · May 5, 2021 · PreprintGenomics
Brain Somatic Mosaicism Network, Yifan Wang, Taejeong Bae, Jeremy Thorpe, Maxwell A. Sherman, Attila Jones, Sean Cho, Kenneth Daily, Yanmei Dou, Javier Ganz, Alon Galor, Irene Lobón, Reenal Pattni, Chaggai Rosenbluh, Simone Tomasi, , Alexej S. Abyzov
This study identifies somatic SNVs in non-cancerous human brain tissues and establishes best practices for detecting low-frequency variants.
Genome biology · Mar 29, 2021Peer-reviewedGenomics
Julia V. Halo, Amanda L. Pendleton, Feichen Shen, Aurélien J. Doucet, Thomas Derrien, Christophe Hitte, Laura E. Kirby, Bridget Myers, Elżbieta Śliwerska, Sarah B. Emery, John V. Moran, Adam R. Boyko, Jeffrey M. Kidd
The paper assembles a Great Dane genome using long-read sequencing, revealing improvements over the Boxer-derived reference and highlighting retrotransposon activity in canine genetic variation.
Proceedings of the National Academy of Sciences · Mar 8, 2021Peer-reviewedGenomics
Xiaowei Zhu, Bo Zhou, Reenal Pattni, Kelly Gleason, Chunfeng Tan, Agnieszka Kalinowski, Steven A. Sloan, Anna-Sophie Fiston-Lavier, Jessica Mariani, Dmitri A. Petrov, Ben A. Barres, Laramie E. Duncan, Alexej S. Abyzov, Hannes S. Vogel, Brain Somatic Mosaicism Network, , Gary W. Mathern
The paper introduces a machine learning method to detect somatic L1 insertions in human brain tissue, revealing their widespread distribution in neurons and glia and potential role in neuropsychiatric diseases.
Nature Neuroscience · Jan 11, 2021Peer-reviewedGenomics
Xuefang Zhao, Sarah B. Emery, Bridget Myers, Jeffrey M. Kidd, Ryan E. Mills
SVelter reconstructs complex structural genomic rearrangements by iteratively rearranging genome regions and scoring them against sequencing data.
bioRxiv · Oct 4, 2015Bioinformatics