This study shows that HIV infection reduces NHE6, leading to endosomal acidification that aids immune evasion by enhancing Nef-mediated MHC-I downmodulation.

iScience · Jul 22, 2026Peer-reviewedCell Biology

Mechanisms of HIV Latency in Hematopoietic Progenitors: GFI1 as a Key Regulator

Jackline A. Onyango, Chen Li, Cuie Chen, W. Miguel Disbennett, Maria Virgilio, Mark M. Painter, Valeri H. Terry, Barkha Ramnani, Joshua D. Welch, Kathleen L. Collins

This study identifies GFI1 as a key regulator of HIV latency in hematopoietic progenitors through transcriptomic analysis and functional assays.

bioRxiv · Feb 20, 2026 · PreprintMicrobiology

Discovery of Alstrom syndrome gene as a regulator of centrosome duplication in asymmetrically dividing stem cells in Drosophila.

Cuie Chen, Yukiko M Yamashita

The paper identifies Alms1a as a regulator of centrosome duplication in asymmetrically dividing Drosophila stem cells and shows its specific requirement in this process.

eLife · Sep 23, 2020Peer-reviewedDevelopmental Biology

A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage

Zsolt G. Venkei, Charlotte P. Choi, Suhua Feng, Cuie Chen, Steven E. Jacobsen, John K. Kim, Yukiko M Yamashita

The paper shows that Klp10A mediates Piwi shuttling between nucleus and nuage during mitosis, linking nuclear and cytoplasmic piRNA silencing arms.

PLoS Genetics · Mar 13, 2020Peer-reviewedDevelopmental Biology