Author

Silke Rimaux

KU LeuvenORCID 0000-0002-1802-2246Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

Annelies StevaertiD· 2 shared Cato MestdaghiD· 2 shared Lieve M. J. NaesensiD· 2 shared Ria Van Berwaer· 2 shared Aitor ValdiviaiD· 1 shared Bert VanmecheleniD· 1 shared Celia EscricheiD· 1 shared Francisco Javier LuqueiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Annelies StevaertORCID

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2 papers

Recent·Most cited

N-benzamides as Influenza Virus Fusion Inhibitors Acting on H1 and H5 Hemagglutinins

Silke Rimaux, Aitor Valdivia, Juan Martín-López, Valeria Francesconi, Celia Escriche, Cato Mestdagh, Ria Van Berwaer, Lieselotte Schurmans, Kaat Verleye, Sam Noppen, Oscar Perlaza Lozano, Annelies Stevaert, Francisco Javier Luque, Lieve M. J. Naesens, Santiago Vázquez

This paper identifies N-benzamides as inhibitors of influenza virus fusion, showing efficacy against H1 and H5 hemagglutinins with low EC50 values and high selectivity.

bioRxiv · Jul 28, 2025 · PreprintMicrobiology

Random mutagenesis of influenza hemagglutinin identifies new sites which modulate its acid-stability and cleavability

Silke Rimaux, M.F. Oliva, Cato Mestdagh, Ria Van Berwaer, Jianjun Chen, Geert Schoofs, Bert Vanmechelen, Joren Stroobants, Maarten Jacquemyn, M. Laporte, Piet Maes, Kurt Vermeire, Kalyan Das, Annelies Stevaert, Lieve M. J. Naesens

This study identifies mutations in influenza hemagglutinin that increase acid-stability and decrease cleavability, with implications for viral transmissibility and vaccine development.

bioRxiv · Jul 25, 2025 · PreprintMicrobiology