Author

Alexis M. Feidler

University of RochesterORCID 0000-0002-1827-6473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Ania Katarzyna MajewskaiD· 2 shared Blanca Lago Solis· 1 shared Britta EngelhardtiD· 1 shared Cassandra E. Lamantia· 1 shared Elizabeth C. PlunkiD· 1 shared Emi NagoshiiD· 1 shared Emily E. Reitz· 1 shared Erik D. VonKaeneliD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersNeuroscience

Ania Katarzyna MajewskaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pericytes Repair Engineered Defects in the Basement Membrane to Restore Barrier Integrity in an in vitro Model of the Blood-Brain Barrier.

Michelle A. Trempel, Yimei Du, Louis P. Widom, Emily E. Reitz, Alexis M. Feidler, Pelin Kasap, Britta Engelhardt, Thomas R. Gaborski, Harris A. Gelbard, Niccolò Terrando, James L. McGrath

Materials Today Bio · Sep 27, 2025Peer-reviewedBioengineering

A Model-Based Hierarchical Bayesian Approach to Sholl Analysis

Erik D. VonKaenel, Alexis M. Feidler, Rebecca L. Lowery, Katherine M. Andersh, Tanzy Love, Ania Katarzyna Majewska, Matthew N. McCall

The paper introduces a hierarchical Bayesian model for Sholl analysis to better handle hierarchical data structures in microglia morphology studies.

Bioinformatics · Mar 19, 2024Peer-reviewedNeuroscience

Noradrenergic signaling controls Alzheimer's disease pathology via activation of microglial β2 adrenergic receptors

Linh Le, Alexis M. Feidler, Leticia Rodrı́guez, MaKenna Y. Cealie, Elizabeth C. Plunk, Herman Li, Kallam Kara-Pabani, Cassandra E. Lamantia, M. Kerry O’Banion, Ania Katarzyna Majewska

This study shows that microglial β2 adrenergic receptors modulate Alzheimer's disease pathology by reducing inflammation and amyloid pathology in mouse models.

bioRxiv · Dec 1, 2023Neuroscience

Rhythmic expression of Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP-PKA signaling

Pedro Machado Almeida, Blanca Lago Solis, Luca Stickley, Alexis M. Feidler, Emi Nagoshi

The paper identifies rhythmic expression of Nf1 in Drosophila mushroom body neurons and shows its role in promoting daytime wakefulness through cAMP-PKA signaling.

Nature Communications · Oct 1, 2021Peer-reviewedNeuroscience