Author

Michelle A. Trempel

University of RochesterORCID 0009-0005-3881-3220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

James L. McGrathiD· 2 shared Louis P. WidomiD· 2 shared Thomas R. GaborskiiD· 2 shared Alexis M. FeidleriD· 1 shared Britta EngelhardtiD· 1 shared Emily E. Reitz· 1 shared Harris A. GelbardiD· 1 shared Lea Vacca MicheliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

James L. McGrathORCID

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2 papers

Recent·Most cited

Cell BiologyLab on a ChipPeer-reviewedJan 1, 2026

Bacterial extracellular vesicles indirectly destabilize a human stem cell-derived blood-brain barrier on-chip through pro-inflammatory stimulation of immune cells

Louis P. Widom, Panteha Torabian, Michelle A. Trempel…·Thomas R. Gaborski

The paper shows that bacterial extracellular vesicles disrupt a BBB on-chip model indirectly via immune cell activation, not directly through BMEC damage.

1 citation

humanspatial transcriptomics

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BioengineeringMaterials Today BioPeer-reviewedSep 27, 2025

Pericytes Repair Engineered Defects in the Basement Membrane to Restore Barrier Integrity in an in vitro Model of the Blood-Brain Barrier.

Michelle A. Trempel, Yimei Du, Louis P. Widom…·James L. McGrath

7 citations

spatial transcriptomicsimaging

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