Terminally Differentiated Influenza-Specific Effector Memory B Cells Circulate after Live Attenuated Influenza Vaccination
Anoma Nellore, Christopher Fucile, Christopher D. Scharer, Jack T. Geer, Jacey D Lemonds, Betty J. Mousseau, Fen Zhou, Esther Zumaquero, Jobaida Akhter, Ellie N. Ivanova, Page Murray, Valeria Estrada Navarro, Paul Goepfert, Ralf Duerr, Ramin S. Herati, , Troy D. Randall
This study identifies circulating HA+ IgDneg memory B cells after LAIV, finding they differ in transcriptional profiles and functional capacity compared to IIV-elicited cells.
bioRxiv · Jan 21, 2026 · PreprintImmunology