Troy D. Randall

This study shows that entinostat enhances CD8+ T cell responses in tumors but only when administered during a specific window after T cell activation, and this effect can be restored by prior oncolytic virus treatment.

This study evaluates two RSV-vectored SARS-CoV-2 vaccines, showing they induce systemic and mucosal immunity and protect against viral challenge and natural infection.

The paper shows IRF1 regulates B cell fate by modulating the IRF4-IRF8 axis, promoting pathogenic effector B cells in SLE.

This study identifies circulating HA+ IgDneg memory B cells after LAIV, finding they differ in transcriptional profiles and functional capacity compared to IIV-elicited cells.

This study shows that acute malaria infection reduces the effectiveness of a low-dose Ebola vaccine by impairing antibody responses in lymph node macrophages, which can be mitigated with higher vaccine doses.

This study shows that intranasal delivery of influenza antigens via a replication-deficient adenovirus induces broader antibody responses and better viral immunity in the respiratory tract compared to systemic delivery.