The paper identifies AQPF, an aquaporin in Aspergillus niger, as facilitating hydrogen peroxide transport across the cell membrane, supporting its role as a signaling molecule in glucose oxidase induction.

Journal of Fungi · Apr 21, 2023Peer-reviewedMolecular Biology

Punctuated loci on chromosome IV determine natural variation in Orsay virus susceptibility of Caenorhabditis elegans strains Bristol N2 and Hawaiian CB4856

Mark G. Sterken, Lisa van Sluijs, Yiru A. Wang, Wannisa Ritmahan, Mitra L. Gultom, Joost A. G. Riksen, Rita J. M. Volkers, Basten L. Snoek, Gorben P. Pijlman, Jan E. Kammenga

The paper identifies two loci on chromosome IV in C. elegans associated with OrV susceptibility, with a single nucleotide polymorphism in cul-6 contributing to the difference between strains.

Journal of Virology · Apr 5, 2021Peer-reviewedGenetics

The genetics of gene expression in a C. elegans multi parental recombinant inbred line population.

Basten L. Snoek, Mark G. Sterken, Harm Nijveen, Rita J. M. Volkers, Joost A. G. Riksen, Philip C Rosenstiel, Hinrich Schulenburg Y, Jan E. Kammenga

The paper uses a multi-parental recombinant inbred line population in C. elegans to study gene expression variation and identifies eQTLs and trans-bands affecting gene expression.

bioRxiv · Mar 4, 2021 · PreprintGenetics

Dissecting the eQTL micro-architecture in Caenorhabditis elegans

Mark G. Sterken, Roel P. J. Bevers, Rita J. M. Volkers, Joost A. G. Riksen, Jan E. Kammenga, Basten L. Snoek

This study maps eQTL in C. elegans RILs across environments, showing higher reproducibility of local eQTL and environmental effects on eQTL micro-architecture.

Frontiers in Genetics · Nov 3, 2020Peer-reviewedGenetics

A multi-parent recombinant inbred line population of Caenorhabditis elegans enhances mapping resolution and identification of novel QTLs for complex life-history traits

Basten L. Snoek, Rita J. M. Volkers, Harm Nijveen, Carola Petersen, Philipp Dirksen, Mark G. Sterken, Rania Nakad, Joost A. G. Riksen, Philip C Rosenstiel, Jana J. Stastna, Bart P. Braeckman, Simon Crawford Harvey, Hinrich Schulenburg Y, Jan E. Kammenga

This study develops a multi-parent recombinant inbred line population of C. elegans to improve QTL mapping resolution and identify novel QTLs for life-history traits.

bioRxiv · Oct 14, 2018 · PreprintGenetics

Contribution of trans regulatory eQTL to cryptic genetic variation in C. elegans

Basten L. Snoek, Mark G. Sterken, Roel P. J. Bevers, Rita J. M. Volkers, Arjèn E. van’t Hof, Rachel Brenchley, Joost A. G. Riksen, Andrew R. Cossins, Jan E. Kammenga

The paper investigates how trans regulatory eQTL contribute to cryptic genetic variation in C. elegans under heat stress and recovery conditions.

BMC Genomics · Jun 29, 2017Peer-reviewedGenetics