Author

Vincenzo Prato

University of LeedsORCID 0000-0002-1887-5556Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Nikita L. GamperiD· 3 shared Frederick JonesiD· 2 shared Sofia Figoli· 2 shared Arthur Silveira PrudenteiD· 1 shared Benito MaffeiiD· 1 shared Char Palfrey· 1 shared Han HaoiD· 1 shared Haxia Gao· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersNeuroscience

Nikita L. GamperORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Junctional Nanodomains Organised by Extended Synaptotagmin-1 Underlie Inflammatory Signalling in Sensory Neurons

Char Palfrey, James Grayston, Xiaoding Zhang, Yiting Gao, Sofia Figoli, Lilly Dougherty, Zhezhuyun Chen, Vincenzo Prato, Frederick Jones, Stephen W. Milne, Haxia Gao, Mark S. Shapiro, Nikita L. Gamper, Shihab Shah

This study identifies Esyt1 as a scaffold organizing ER-PM nanodomains that regulate inflammatory pain signaling through Ca2+-dependent interactions.

bioRxiv · Oct 29, 2026 · PreprintNeuroscience

ESCRT-I Inhibition Protects against NMDAR Hypofunction and Restores Synaptic Homeostasis in a Cellular Model of Schizophrenia

Mohamed Fouad Shalaby, Vincenzo Prato, Jacobo Elíes, Nikita L. Gamper, Samantha Louise McLean, Sriharsha Kantamneni

The paper shows that inhibiting ESCRT-I prevents NMDAR hypofunction and restores synaptic homeostasis in a schizophrenia model caused by PCP exposure.

bioRxiv · Sep 13, 2026 · PreprintNeuroscience

Peripheral gating of pain by glial endozepine

Xinmeng Li, Arthur Silveira Prudente, Vincenzo Prato, Xianchuan Guo, Han Hao, Frederick Jones, Sofia Figoli, Pierce N. Mullen, Yujin Wang, Raquel Tonnello, Sang Hoon Lee, Shihab S. Shah, Benito Maffei, Temugin Berta, Xiaona Du, Nikita L. Gamper

This study identifies DBI as a glial messenger that modulates mechanosensation through GABAA receptor interaction in DRG, offering a new therapeutic target for pain management.

bioRxiv · Nov 20, 2023 · PreprintNeuroscience