Temugin Berta

History of opioid use disorder correlates with altered neuroimmune signatures in the human dorsal root ganglia

The paper examines molecular and physiological changes in dorsal root ganglia from individuals with and without opioid use disorder, identifying altered neuroimmune signatures and sensitized sensory neurons.

Nav1.5 expressed in TrkB+ sensory neurons mediates paclitaxel-induced mechanical pain hypersensitivity

This study identifies Nav1.5 in TrkB+ sensory neurons as a driver of paclitaxel-induced mechanical pain hypersensitivity in mice, with potential translational relevance to humans.

Sympathetic Control of Sensory Neuron Fate and Function

This study shows that sympathetic innervation is critical for sensory neuron survival and function, with norepinephrine and macrophages playing protective roles.

Satellite glial GPR37L1 regulates maresin and potassium channel signaling for pain control

This study identifies GPR37L1 in satellite glial cells as a regulator of pain control through interactions with potassium channels and maresin 1, showing its role in neuropathic pain resolution.

Peripheral gating of pain by glial endozepine

This study identifies DBI as a glial messenger that modulates mechanosensation through GABAA receptor interaction in DRG, offering a new therapeutic target for pain management.

Resolvin D3 controls mouse and human nociceptive functions and preclinical progression of psoriasis

This study shows that resolvin D3 reduces skin inflammation and itch in psoriasis models by inhibiting nociceptive functions in both mice and human neurons.

Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn

The paper identifies the transcriptomic profile of somatostatin-expressing interneurons in the spinal dorsal horn of mice, revealing novel genes and pathways relevant to mechanical pain.