Arthur Silveira Prudente

The paper examines molecular and physiological changes in dorsal root ganglia from individuals with and without opioid use disorder, identifying altered neuroimmune signatures and sensitized sensory neurons.

This study identifies Nav1.5 in TrkB+ sensory neurons as a driver of paclitaxel-induced mechanical pain hypersensitivity in mice, with potential translational relevance to humans.

This study shows that sympathetic innervation is critical for sensory neuron survival and function, with norepinephrine and macrophages playing protective roles.

This study identifies DBI as a glial messenger that modulates mechanosensation through GABAA receptor interaction in DRG, offering a new therapeutic target for pain management.