Jitendra Thakur

This study generates genomic and epigenomic maps of mouse centromeres and pericentromeres using long-read sequencing and epigenetic analyses, revealing satellite DNA composition and chromatin state differences.

The paper analyzes DNA satellite and chromatin organization in mouse centromeres and pericentromeres, revealing sequence diversity and chromatin structure variations.

The paper investigates how CTCF-mediated chromatin insulation and structure regulate escape from X chromosome inactivation in mouse cells, showing that CTCF binding and domain organization are critical for maintaining XCI.

The paper shows boundary-associated RNAs enhance TAD insulation by promoting CTCF clustering at TAD boundaries.

This study shows that Firre RNA has trans-acting effects on the inactive X chromosome, affecting histone modifications, PRC2 complex components, and chromatin structure.

The paper shows RNA stabilizes heterochromatin domains by acting as a structural scaffold, using CUT&RUN.RNase to study RNA's role in chromatin organization.