Author

Mingwei Lian

Southern University of Science and TechnologyORCID 0000-0002-1901-6366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Chang LiuiD· 1 shared Chuanyu LiuiD· 1 shared Gangjian QiniD· 1 shared Haibo NiiD· 1 shared Haocheng LuiD· 1 shared Jiajun YaoiD· 1 shared Jing CheniD· 1 shared Kang Ouyang· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperDevelopmental Biology

Chang LiuORCID

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2 papers

Recent·Most cited

PDE3A2 modRNA Fine-Tunes Nuclear cAMP Microdomains and Reverses Pathological Cardiac Hypertrophy

Wenjing Xiang, Mingwei Lian, Qiuyun Guan, Xingsheng Sun, Supeng Li, Haocheng Lu, Gangjian Qin, Yang K. Xiang, Haibo Ni, Ying Wang

This study develops PDE3A2-modRNA to restore nuclear cAMP microdomain regulation, reversing pathological cardiac hypertrophy in a mouse model.

bioRxiv · Sep 30, 2025 · PreprintPathology

A single-cell 3D spatiotemporal multi-omics atlas from Drosophila embryogenesis to metamorphosis

Mingyue Wang, Qinan Hu, Zhencheng Tu, Lingshi Kong, Jiajun Yao, Rong Xiang, Zhan Chen, Yan Zhao, Yanfei Zhou, Tengxiang Yu, Yuetian Wang, Zihan Jia, Kang Ouyang, Xianzhe Wang, Yinqi Bai, , Yuhui Hu

The paper constructs a 3D spatiotemporal multi-omics atlas of Drosophila development, revealing gene regulatory networks and cell type dynamics across embryogenesis to metamorphosis.

bioRxiv · Feb 6, 2024 · PreprintDevelopmental Biology