Thomas D. Gilmore

This study shows that hosting different algal symbionts in corals affects immune responses and stress tolerance, with trade-offs in survival under heat and pathogen challenges.

This study examines how heat and nitrate affect symbiosis in sea anemones, finding that while nitrate can temporarily buffer thermal stress, combined stressors lead to holobiont failure.

This study examines microbiome recovery in a cnidarian host after antibiotic treatment, showing that symbiotic Aiptasia reestablishes bacterial communities while aposymbiotic Aiptasia does not, with implications for host-microbe interactions.

This study compares NF-κB activity in two jellyfish species, showing differences in transcriptional activation and subcellular localization.

This study investigates immune regulation in symbiotic and aposymbiotic coral tissue using multiomic approaches, revealing compartmentalized immune suppression in specific cell types during symbiosis.

This study shows antibiotic treatment reduces microbial diversity and slows regeneration in two cnidarian species, highlighting the role of microbiomes in regeneration.

The paper introduces CoRec, a method to profile TF-COF complexes, revealing KAT-TF interactions and their role in H3K27ac regulation.

AutoMorFi automates whole-image morphometric analysis, generating over 47 measurements per cell quickly and enabling new discoveries across diverse biological samples.

This study identifies a conserved core region in NEMO essential for conformational changes and liquid-liquid phase separation in the NF-κB signaling pathway.

This study shows that nutrient deprivation affects gene expression, immunity, and pathogen susceptibility differently in symbiotic and aposymbiotic cnidarians.

This paper uses CRISPR/Cas9 to disrupt a promoter element in 293T cells, eliminating NEMO expression and canonical NF-κB signaling while preserving non-canonical signaling.

The paper investigates the role of NF-κB in cnidarian-algal symbiosis and thermotolerance in Aiptasia and Pocillopora damicornis, showing differential expression and effects on survival and bleaching.