Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of secretory proteins
Haruka Sato, Jun Hatakeyama, Takuji Iwasato, Kimi Araki, Nobuhiko Yamamoto, Kenji Shimamura
The paper identifies VGF as a thalamus-derived factor essential for maintaining layer 4 neuron numbers in mouse sensory cortices, highlighting thalamocortical axons' role in shaping cortical cytoarchitecture through area-specific secretory protein supply.
eLife · Mar 15, 2022Peer-reviewedNeuroscience