Author

Ruth Serra-Moreno

University of RochesterORCID 0000-0002-1923-6414Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

Ana Silvia Gonzalez-ReicheiD· 1 shared Andreas PichlmairiD· 1 shared Armin EnsseriD· 1 shared Arne CordsmeieriD· 1 shared Christoph JungiD· 1 shared Dorota KmiećiD· 1 shared Emilia Mia SordilloiD· 1 shared Fabian ZechiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Ana Silvia Gonzalez-ReicheORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedSep 23, 2026

SARS-CoV-2 Defective Viral Genomes from Distinct Genomic Regions Drive Divergent Interferon Responses

Justin W Brennan, Simone Spandau, Jiayu Xu…·Yan Sun

This study shows that SARS-CoV-2 defective viral genomes from different genomic hotspots induce divergent interferon responses, with hotspot B DVGs strongly stimulating IFN responses and hotspot A DVGs not.

DOI 10.1371/journal.ppat.1014099

humanbulk RNA-seq

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MicrobiologyiSciencePeer-reviewedJun 20, 2025

SARS-CoV-2 Omicron Envelope T9I adaptation confers resistance to autophagy

Susanne Klute, Rayhane Nchioua, Arne Cordsmeier…·Konstantin M. J. Sparrer

The paper shows that the T9I mutation in the SARS-CoV-2 E protein confers autophagy resistance in Omicron variants, contributing to their spread.

9 citationstop 3%

virusexperimental assay

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