This study shows that SARS-CoV-2 defective viral genomes from different genomic hotspots induce divergent interferon responses, with hotspot B DVGs strongly stimulating IFN responses and hotspot A DVGs not.

DOI 10.1371/journal.ppat.1014099

humanbulk RNA-seq

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MicrobiologyJournal of VirologyPeer-reviewedMar 24, 2026

A Respiratory Syncytial Virus trailer sequence modulates viral replication and copy-back defective viral genome generation and propagation kinetics

Justin W Brennan, G.C. Wang, Sarah Connor…·Yan Sun

2 citationstop 3%

virusexperimental assay

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GenomicsbioRxivPreprintApr 9, 2025

Two telomere-to-telomere genome assemblies and comparisons revealed the conserved key genes associated with sugar accumulation in Rubus genus

Xiaopeng Li, Xu Han, Shoucheng Liu…·Junhui Zhou

1 citation

plant (other)whole-genome sequencing

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BioinformaticsGigaSciencePeer-reviewedJan 1, 2023

ViReMa: A Virus Recombination Mapper of Next-Generation Sequencing data characterizes diverse recombinant viral nucleic acids

Stephanea L. Sotcheff, Yiyang Zhou, Jason Yeung…·Andrew L. Routh

ViReMa is updated to detect recombination events in long-read sequencing data and reports various recombinant species in different viral contexts.

33 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky