NeurosciencebioRxivPreprint
LRP1 mediates leptin transport by coupling with the short-form leptin receptor in the choroid plexus
Aykut Göktürk Üner, Won‐Mo Yang, Mincheol Kang…·Young‐Bum Kim
This study identifies LRP1 as a mediator of leptin transport across the blood-CSF barrier in the choroid plexus, coupled with the short-form leptin receptor, and shows its deletion leads to leptin resistance and obesity.
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