Lei Cheng

This study identifies new photobiocatalytic C-C couplings by combining PLP enzymes with photocatalysts, enabling the synthesis of non-canonical amino acids through directed evolution.

This paper develops engineered PLP-dependent biocatalysts for stereodivergent synthesis of non-canonical amino acids with complex stereochemical arrays, achieving high stereoselectivity and yield.

This paper develops a biocatalytic method using engineered PLP enzymes to selectively synthesize L- and D-amino acids from alkyl radicals.